Fred S. Apple, PhD

fred apple2018 Outstanding Contributions Through Service to the Profession of Clinical Chemistry

2009 Award for Outstanding Contributions to Clinical Chemistry in a Selected Area of Research

Dr. Apple is medical director of clinical laboratories, clinical chemistry, point-of-care testing, and clinical and forensic toxicology laboratories at the Hennepin County Medical Center; professor of laboratory medicine and pathology at the University of Minnesota School of Medicine; and forensic toxicology consultant to the Hennepin County Medical Examiner’s Office in Minneapolis. Dr. Apple’s research interests have centered in the areas of cardiac biomarkers in acute coronary syndrome and heart failure, as well as forensic toxicology. His CLIA-certified research laboratory is the “Cardiac Biomarkers Trials Lab” at the Minneapolis Medical Research Foundation of Hennepin County Medical Center/Hennepin Healthcare. Dr. Apple has served as an associate editor of Clinical Chemistry for the past 20 years. He also serves as a member of the global task force on the universal definition of myocardial infarction and myocardial injury, chair of the International Federation of Clinical Chemistry task force on clinical application of cardiac biomarkers, member of the the Academy of Diagnostics & Laboratory Medicine committee on laboratory medicine practice guidelines for myocardial infarction and heart failure, and member of the the Association for Diagnostics & Laboratory Medicine (formerly AACC) Clinical Societies Collaboration Committee. He is on the steering committee of the British Heart Foundation HighSTEACS trial. He is the principal investigator of the UTROPIA and CONTRAST studies. He has also served on the Institute of Medicine’s committee on biomarkers as surrogate endpoints of chronic disease risk and on the National Heart, Lung, and Blood Institute working group for onsite tools and technologies for clinical cardiovascular research and point-of-care. He is the program director of the clinical chemistry COMACC fellowship at the Hennepin County Medical Center.